本科组（共1人） 学科 医科 姓名 田煜 年级 2011级本科 科研学术成果 第一作者身份成果： 发表学术论文情况 1.Tian Y, Lu M, Yue W, et al. TFIIB-Related Factor 2 Is Associated with Poor Prognosis of Nonsmall Cell Lung Cancer Patients through Promoting Tumor Epithelial-Mesenchymal Transition[J]. BioMed research international, 2014, 2014.(SCI:2.88) 2.田煜.《医学生人文医学教育浅论》.健康山东杂志.380(2013):43.(期刊杂志） 3.田煜.《小小中国梦 拳拳医者心》.人民网.9(2013):43.（报刊杂志） 4.田煜.《美国游学随感》.齐鲁医院院报.385(2013).（报刊杂志） 5.田煜.《用青春呵护健康生命》.齐鲁医院院报.385(2013).（报刊杂志）
硕士组（共3人）
学科 医科 姓名 年级 科研学术成果 第一作者身份成果： 发表学术论文情况： 1. Wang YW, Chen X, Gao JW, Zhang H, Ma RR, Gao ZH, Gao P. High expression of cAMP-responsive element-binding protein 1 (CREB1) is associated with metastasis, tumor stage and poor outcome in gastric cancer. Oncotarget. 2015 Mar 18. [Epub ahead of print] (SCI收录， IF= 6.402) 2. Wang YW, Shi DB, Chen X, Gao C, Gao P. Clinicopathological Significance of MicroRNA-214 in Gastric Cancer and Its Effect on Cell Biological Behaviour. PLoS One. 2014 Mar 10;9(3):e91307. doi: 10.1371/journal.pone.0091307. eCollection 王亚文 2009级硕士 2014. ( SCI收录, IF=4.015) 3. Wang YW, Shi DB, Liu YM, Sun YL, Chen X, Xiang S, Fu Q, Wei JM, Gao P. Aberrant expression of CD227 is correlated with tumor characteristics and invasiveness of breast carcinoma. J Cancer Res Clin Oncol. 2014 Aug;140(8):1271-81. ( SCI收录， IF= 2.833) 非第一作者身份成果： 发表学术论文情况 1. Xing AY, Wang YW, Su ZX, Shi DB, Wang B, Gao P. Catenin-𝛅1, negatively regulated by miR-145, promotes tumour aggressiveness in gastric cancer. J Pathol. 2014 Dec 3. doi: 10.1002/path.4495. [Epub ahead of print] (第二作者，SCI收录， IF= 7.224) 2. Xiang S, Liu YM, Chen X, Wang YW, Ma RR, Wu XJ, Peng Gao. ZEB1 expression is correlated with tumor metastasis and reduced prognosis of breast carcinoma in Asian patients. Cancer Invest. 2015 Feb 19; Accepted; ID: 1022258 DOI:10.3109/07357907.2015.1022258 (第四作者，SCI收录， IF= 2.094) 承担科研课题情况： 1 2014年国家级大学生创新创业训练计划（项目负责人，创新训练，项目名：miR-489与乳腺癌耐药关系及其调控机制研究，编号201410422124，参与人：王亚文、高继伟，2014年5月-2015年5月，在研，教育部） 2. 2012年度山东大学大学生科技创新基金（项目负责人，项目名：胃癌中miR-214作用机制的研究，编号2012384，重点资助，参与人：王亚文、石端博，2012年5月-2013年5月，已结题，山东大学） 3. 2011年度齐鲁医学班学生科技创新基金项目（项目负责人，项目名：胃癌中miR-214异常表达的研究，编号M2011e19，参与人：王亚文、石端博、付强、隋翔宇，2011年12月-2013年12月，已结题，山东大学） 4. 2012年度齐鲁医学班学生科技创新基金项目（A等资助，项目组第四位，项目名：胃癌中miR-96异常表达及其作用机制的研究，参与人：高继伟、石端博、高超、王亚文，2012年11月-2014年11月，在研，山东大学） 医科 万淼 2014级硕士 第一作者身份成果： 发表学术论文情况： M. Wan, Z. Meng, H. Lou, L. Liu. Practical and Highly Selective C-H Functionalization of Structurally Diverse Ethers. Angew. Chem. Int. Ed. 2014, 53（50）, 13845-13849.（SCI收录，IF=11.336） 医科 李双双 2013级硕士 第一作者身份成果： 发表学术论文情况： 1. Li S, Zhang M, Tian H, Liu ZL, Yin X, Xi B. Preterm birth and risk of type 1 and type 2 diabetes: systematic review and meta‐analysis. Obesity Reviews, 2014, 15(10): 804-811. (SCI收录, IF= 7.859) 2. Li S, Xi B. Preterm birth is associated with risk of essential hypertension in later life. International journal of cardiology, 2014, 172(2): e361-e363. （SCI收录; IF= 6.175） 3. Li S, Miao S, Huang Y, Liu ZL, Tian H, Yin X, Tang WH, Steffen LM, Xi B. Fruit intake decreases risk of incident type 2 diabetes: an updated meta-analysis. Endocrine, 2015, 48: 454-460. (SCI收录, IF= 3.527) 非第一作者身份成果： 1. Xi B, Zhang M, Zhang T, Li S, Lyn M. Steffen. Simplification of childhood hypertension definition using blood pressure to height ratio among US youths aged 8–17years, NHANES 1999–2012. International journal of cardiology, 2015, 180: 210-213. (SCI收录, IF= 6.175) 2. Xi B, Li H, Li S, Mi J. Recent prevalence of hypertension among Chinese children and adolescents based on 2010 China national blood pressure references. International journal of cardiology, 2014, 174(3): 870-871. (SCI收录, IF= 6.175) 3. Xi B, Huang Y, Reilly K H, Li S, Zheng R, Maria T. Barrio-Lopez, Miguel A. Martinez-Gonzalez, Zhou DH. Sugar-sweetened beverages and risk of hypertension and CVD: a dose–response meta-analysis. British Journal of Nutrition, 2015, 113; 709-717. (SCI收录, IF= 3.342) 4. Xi B, Li S, Liu Z, Tian H, Yin X, Huai PC, Tang WH, Zhou DH, Lyn M. Steffen. Intake of fruit juice and incidence of type 2 diabetes: a systematic review and meta-analysis. PloS one, 2014, 9(3): e93471. (SCI收录, IF= 3.534) 5. Zhou DH, Yu HB, He F, Reilly K H, Zhang JL, Li S, Zhang T, Wang BZ, Ding Y, Xi B. Nut consumption in relation to cardiovascular disease risk and type 2 diabetes: a systematic review and meta-analysis of prospective studies. American journal of clinical nutrition. 2014, 100(1): 270-277. (SCI收录, IF= 6.918) 6. Xi B, Zhang M, Zhang T, Liang Y, Li S, Steffen LM. Hypertension screening using blood pressure to height ratio. Pediatrics. 2014, 134(1): e 106-111. (SCI收录, IF= 5.297)
博士组（共4人）
学科 姓名 李晓杨 年级 2011级博士 发表学术论文情况： 1. Li X, Inks ES, Li X, Hou J, Chou CJ, Zhang J, Jiang Y, Zhang Y, Xu W. Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity. J Med Chem. 2014; 57(8):3324-3334. (SCI收录，影响因子：5.480) 2. 3. Li X, Hou J, Li X, Jiang Y, Liu X, Mu W, Jin Y, Zhang Y, Xu W. Eur J Med Chem. 2015; 7(89):628-37. (SCI收录，影响因子：3.432) Li X, Zhang J, Xie Y, Jiang Y, Yingjie Z, Xu W. Progress of HDAC inhibitor panobinostat in the treatment of cancer.Curr Drug Targets. 2014; 15(6):622-634. (SCI收录，影响因子: 3.541) 4. Li X, Xu W. HDAC1/3 dual selective inhibitors New therapeutic agents for the potential treatment of cancer. Drug Discov Ther. 科研学术成果 2014; 8(5):225-8. (MEDLINE收录, 核心期刊) 王晓杰 2010级博士 第一作者身份成果： 发表学术论文情况： 1. Wang Xiaojie, Li Jiang, Yi Fan. HDAC4 Selectively Contributes to Podocyte Injury in Diabetic Nephropathy. Kidney international, 86(2014): 712-725 (SCI收录， IF=8.52) 2. Wang Xiaojie, Yi Fan, Implication of Pattern-recognition Receptors in Cardiovascular Diseases. Antioxid Redox Sign 2014 Nov 11. [Epub ahead of print] (SCI收录，IF=7.71) 3 .Wang Xiaojie, Wei XB, Pang Q, Yi Fan. Histone deacetylases and their inhibitors: molecular mechanisms and therapeutic implications in diabetes mellitus, Acta Pharmaceutica Sinica B 2(2012):387-395 4.王晓杰，易凡 Zn2+依赖型组蛋白去乙酰化酶在糖尿病肾病大鼠中的表达及作用 中国科技论文在线 http://www.paper.edu.cn/html/releasepaper/2013/02/222/ 非第一作者身份成果： 1 .Shang Jin, Wan Qiang, Wang Xiaojie, Duan Yiqi, Yi Fan. Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy. Free Radic Biol Med. 2015 Feb; (SCI IF:5.71) 2. Du P, Fan B, Han H, Zhen J, Shang J, Wang Xiaojie, Li X, Shi W, Tang W, Bao C, Wang Z, Zhang Y, Zhang B, Wei X, Yi Fan. NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney International, 84(2013). (SCI IF:8.52) 3 .Li X, Li FL, Chu YL, Wang Xiaojie, Zhang HY, HU YY, Zhang Y, Wang ZY, Jian WC, Zhang XM, Yi Fan. NOD2 Deficiency Protects against Cardiac Remodeling after Myocardial Infarction in Mice. Cell Physiol Biochem 32(2013) :1857-1866. ( SCI IF: 3.48) 邢爱艳 2012级博士 第一作者身份成果： 1. Xing A, Wang Y, Su Z, Shi D, Wang B, Gao P. Catenin-δ1, negatively regulated by miR-145, promotes tumour aggressiveness in gastric cancer. J Pathol. 2014 Dec 3. doi: 10.1002/path.4495. [Epub ahead of print](SCI收录, IF=7.330) 2.Gao P, Xing AY, Zhou GY, Zhang TG, Zhang JP, Gao C, Li H, Shi DB. The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer.Oncogene. 2013 Jan 24;32(4):491-501. (并列第一位，SCI收录, IF=8.559) 3.Xing AY, Wang B, Shi DB, Zhang XF, Gao C, He XQ, Liu WJ, Gao P. Deregulated expression of miR-145 in manifold human cancer cells.Exp Mol Pathol. 2013 Aug;95(1):91-7. (SCI收录, IF=2.881) 4.Xing AY, Shi DB, Liu W, Chen X, Sun YL, Wang X, Zhang JP, Gao P. Restoration of chemosensitivity in cancer cells with MDR phenotype by deoxyribozyme, compared with ribozyme.Exp Mol Pathol. 2013 Jun;94(3):481-5.(SCI收录, IF=2.881) 非第一作者身份成果： 1. Wang K, Wang B, Xing AY, Xu KS, Li GX, Yu ZH. Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells. J Cancer Res Clin Oncol.2014 Oct 31[Epub ahead of print] (第三位， SCI收录，IF=3.009) 2. Gao P, Wei JM, Li PY, Zhang CJ, Jian WC, Zhang YH, Xing AY, Zhou GY Screening of deoxyribozyme with high reversal efficiency against multidrug resistance in breast carcinoma cells. J Cell Mol Med，2011 Oct;15(10):2130-8. （第七位，SCI收录，IF=3.698） 3. Wang B, Li GX, Zhang SG, Wang Q, Wen YG, Tang HM, Zhou CZ, Xing AY, Fan JW, Yan DW, Qiu GQ, Yu ZH, Peng ZH. Biglycan expression correlates with aggressiveness and poor prognosis of gastric cancer. Exp Biol Med. 2011，236(11):1247-53.（第八位， SCI收录，IF=2.226） 侯旭奔 2012博士 第一作者身份成果： 发表学术论文情况： 1. Xuben Hou, Jintong Du, Renshuai Liu, Yi Zhou, Minyong Li, Wenfang Xu, Hao Fang*. Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8. J. Chem. Inf. Model., 2015, Publish online, DOI: 10.1021/ci500762z. (影响因子4.06) 2. Xuben Hou, Rong Li, Kangshuai Li, Xiao Yu, Jin-peng Sun and Hao Fang*. Fast Identification of Novel Lymphoid Tyrosine Phosphatase Inhibitors Using Target-Ligand Interaction-Based Virtual Screening. J. Med. Chem. 2014, 57, 9309−9322. (影响因子5.2)
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